An Integrated Path to Heart, Blood Pressure, and Brain Health
August 22, 2025 – Steve Bruner

An Integrated Path to Heart, Blood Pressure, and Brain Health
Why a foundation like Everest Earth & Sea™, plus Vintage Resveratrol 100% and Omega-3s, makes sense—alongside your doctor’s care
High blood pressure (hypertension) quietly strains the heart, scars blood vessels, and raises the odds of heart attack, stroke, kidney disease, and cognitive decline. Current public-health guidance is unambiguous: control blood pressure early and steadily to reduce these risks. The CDC and American Heart Association both underscore hypertension as a leading driver of cardiovascular events and strokes, and they note downstream risks to kidneys and brain health as blood vessels are damaged over time. CDCwww.heart.org+1
At Natural Biology, we advocate integrated medicine: work with your physician, take medications when indicated, optimize lifestyle (DASH/Mediterranean-style nutrition, movement, sleep, stress care), and consider targeted, evidence-informed supplementation. Three tools that pair well with that plan are:
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A broad, food-forward multi-nutrient base (Everest Earth & Sea™)
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Omega-3s (EPA/DHA)
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Vintage Resveratrol 100% (whole-grape–based polyphenols, including OPCs)
Below is how each can support heart, blood pressure, and mental health—as complements to your clinician’s plan.
1) Build the foundation: comprehensive micronutrients (Everest Earth & Sea™)
Everest Earth & Sea™ is designed as a whole-food–leaning multi-nutrient system (vitamins, minerals, antioxidants, adaptogens, probiotics, and co-factors). Think of it as nutrition “infrastructure” that helps cover common gaps so heart-protective habits can work better. NATURAL BIOLOGY
Why this matters for blood pressure and the heart:
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Mineral balance helps vessels relax. Robust evidence shows higher potassium intake lowers blood pressure, and magnesium supplementation produces modest BP reductions, especially in people with inadequate intake. Even small drops (2–4 mmHg) matter at the population level for reducing cardiovascular events. PubMedAHA JournalsFrontiers
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Brain & cognition in older adults: Large randomized COSMOS-Mind trials found a daily multivitamin-mineralimproved measures of global cognition and memory over 1–3 years in older adults (benefits were most pronounced in participants with cardiovascular disease). While not a cure, this suggests a solid micronutrient base may support healthy cognitive aging. Alzheimer's & Dementiaajcn.nutrition.orgScienceDirect
Takeaway: a comprehensive multi—like Everest Earth & Sea™—won’t replace meds or diet, but it can help restore nutrient sufficiency that supports vascular tone, heart rhythm, and brain energy metabolism. NATURAL BIOLOGY
2) Reduce vascular strain and support mood: Omega-3s (EPA/DHA)
Omega-3s (EPA/DHA) support endothelial function, triglyceride lowering, and blood-pressure modulation:
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Blood pressure: A 2022 dose-response meta-analysis of randomized trials found ~2–3 g/day of combined EPA+DHA was optimal for lowering BP, with larger effects in people with hypertension or lipid disorders. Typical reductions were a few mmHg, which is clinically meaningful alongside lifestyle and medications. PubMedAHA Journals
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Lipids: The AHA notes prescription-strength omega-3s (4 g/day) lower triglycerides by ~20–30% in people with high levels. (OTC supplements are not substitutes for prescription therapy in severe hypertriglyceridemia, but quality OTC omega-3s can still help you reach daily EPA+DHA targets for general heart support.) AHA Journalswww.heart.org
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Mental health: Meta-analyses suggest EPA-dominant formulas (≥60% EPA, often ≤1 g/d of EPA) can modestly improve depressive symptoms in adults. Effects on anxiety are mixed but suggest potential benefit at higher doses in clinical populations. Omega-3s are not psychiatric medications, yet they can be a useful adjunct under clinician guidance. PubMedPMC
Takeaway: Pairing 2–3 g/day EPA+DHA with your lifestyle and medical plan can shave a few mmHg off BP and support cardiometabolic and mood pathways. PubMed
3) Add polyphenol support: Vintage Resveratrol 100% (whole-grape actives, incl. OPCs)
Vintage Resveratrol 100% provides a whole-grape matrix—including trans-resveratrol and oligomeric proanthocyanidins (OPCs)—rather than isolated resveratrol alone. This spectrum targets oxidative stress and endothelial function, both relevant to healthy blood pressure and brain perfusion. NATURAL BIOLOGY
What the evidence shows:
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Grape seed/OPC polyphenols: Multiple meta-analyses of randomized trials report small but significant reductions in systolic (~1–5 mmHg) and diastolic BP with grape-derived polyphenols, particularly in younger, overweight, or metabolically at-risk adults. PLOSPMC
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Resveratrol & the brain: Human data are heterogeneous; several trials suggest select cognitive benefits (e.g., memory measures or neurovascular coupling) while others show no effect—dose and matrix likely matter. Consider it adjunctive support for vascular and neuronal health, not a stand-alone therapy. Oxford AcademicPMC
Takeaway: Whole-grape polyphenols (resveratrol + OPCs) can nudge BP and vascular function in the right direction, complementing diet and omega-3s. PMC
Why blood pressure control protects your brain and kidneys
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Stroke & heart disease: Hypertension drives atherosclerosis and vessel damage; most people who suffer a first stroke had high blood pressure. Control it early and consistently. www.heart.org
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Dementia/cognitive decline: Major scientific bodies identify mid-life hypertension as a key modifiable risk factor for later-life cognitive impairment and dementia; randomized data and guideline updates increasingly emphasize BP control to protect brain health. ScienceDirectVerywell Health
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Kidney disease: Diabetes and high blood pressure are the two most common causes of chronic kidney disease; managing BP is among the most important steps to slow kidney damage. NIDDK+1
How to put this together (the integrated plan)
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See your clinician. Get a proper diagnosis, home BP monitor, and start/continue medications when indicated. Today’s guidelines favor sooner treatment if lifestyle alone doesn’t normalize BP. Verywell Health
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Lifestyle first, always:
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DASH/Mediterranean eating (potassium-rich plants, adequate magnesium, omega-3–rich seafood, low sodium).
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Move daily, sleep 7–9 hours, manage stress, limit/avoid alcohol per your clinician’s advice. Verywell Health
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Targeted supplementation (with your doctor’s okay):
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Everest Earth & Sea™ as your nutrient base. NATURAL BIOLOGY
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Omega-3s (EPA+DHA) -Norwegian Omega 3 & Arctic Ocean Krill Oil to reach ~2–3 g/day combined for BP support; particularly if triglycerides are high per your physician. PubMedwww.heart.org
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Vintage Resveratrol 100% (whole-grape polyphenols) for adjunct vascular support; remember effects are modest and work best with diet, meds, and movement. PLOS
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Bottom line
Medications + lifestyle are the non-negotiables for blood pressure and heart protection. Layering a comprehensive multi-nutrient base, omega-3s, and whole-grape polyphenols can provide incremental, evidence-aligned support for your heart, blood pressure, and brain, and help defend the kidneys—all within an integrated medicine approach you personalize with your physician. www.heart.org
Important medical disclaimer
This article is for education only and is not medical advice. Always consult your physician before starting any supplement, especially if you take prescription medications (blood thinners, blood-pressure drugs, diabetes meds, etc.) or have medical conditions. For high blood pressure, follow your clinician’s plan—including prescription medications when indicated. Supplements are adjuncts, not replacements, for professional care and healthy lifestyle. www.heart.org
Product reference pages (composition/intent): Everest Earth & Sea™ and Vintage Resveratrol 100% descriptions/ingredient profiles are available on Natural Biology’s site. Clinical health claims in this article are grounded in external peer-reviewed or public-health sources cited above.
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